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Talc Products and Ovarian Cancer

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There is currently talcum talc powder lawsuit where women, that have a history of usage of talc products; Johnson’s® Baby Powder and Shower to Shower Body Powder on their genitals, were diagnosed with ovarian cancer. Scientific studies and the World Health Organization have determined a link between long term genital use of talcum powder and cancer. In June 2013, Cancer Prevention Research shared a study which determined females with a history of using talc-containing powder on their genital areas have a twenty to thirty percent increased risk of developing ovarian cancer. Presented with scientific determination, expert testimony, and factual evidence, a court in St. Louis determined that Johnson & Johnson neglected to warn people about the risk of ovarian cancer connected with the genital area use of its talc-based powders. Company documents shared during the trial indicate that Johnson & Johnson was aware of the studies and tried to discredit them. The jury awarded $72 million in damages to the family of a woman who succumbed to ovarian cancer and had a history of using Johnson’s® Baby Powder and Shower to Shower® Body Powder.

The Correlation Between Talcum Powder & Ovarian Cancer
The earliest scientific research to describe a potential link between talc and ovarian cancer was reported in 1971. Chronicled were pathology examinations of tissue samples from 10 women diagnosed with ovarian cancer. The scientists noticed talc in every one of the tissue samples, a sign that each woman’s talc containing powder had migrated from her external genitalia to her internal organs. Eleven years later, an study conducted by Dr. Daniel Cramer of Brigham & Women’s Hospital showed a statistical connection between a history of genital talc containing product use and ovarian cancer.

Results of the study reveal an increase in risk of ovarian cancer. An article about Dr. Cramer’s study appeared in the August 1982 issue of The New York Times. The research examined the health history and genital talc usage of 215 women who were diagnosed with ovarian cancer and measured them to women who did not use talc. The results showed an association between the genital use of talc and ovarian cancer. Over the continuing years, more than fifteen studies have shown that long term, frequent, genital application of talc-containing products by women created a 33% increase in the risk of developing ovarian cancer. Though a few studies have suggested no connection between the usage of baby powder and ovarian cancer, these studies have been discredited for not taking into account both duration and frequency of talc usage which is the only true measurement of a woman’s exposure to talc.

Asbestos and Ovarian Cancer
During the formal discovery portion of recent litigation involving Johnson & Johnson, information has come to light that expose company concerns over asbestos contaminated talc dating back several decades and that the company fought an intense campaign to hide test results, scientific papers and other information that talc in its Baby Powder® contained asbestos. The fact that Johnson & Johnsons Baby Powder and Shower to Shower® body powder, as well as other brands of talc containing powders could have been contaminated with asbestos, has re-focused much of the nationwide litigation. Though most asbestos lawsuits and claims focus on employment, military and industrial-related risk to asbestos, and asbestos contaminated products as causing mesothelioma, the ever increasing recent litigation is now focused on the link between asbestos, talc and ovarian cancer.

Focused on both the factual and scientific connections between risk to asbestos contaminated talc powders and the appearance of ovarian cancer, the legal effort is continuing to evolve and being joined by hundreds women that have been diagnosed with ovarian cancer.

More News About Ovarian Cancer
Ovarian Cancer and The Subtypes
Ovarian cancer is a general phrase which includes several subtypes which are known and distinguishable by their different characteristics and their location. Most ovarian cancer is found in the epithelium, that is the layer of tissue that surrounds the ovary. Approximately 90% of all ovarian cancers are found in the epithelium. There are numerous subtypes of epithelial ovarian cancers including serous cell and endometrioid.

An additional subtype is peritoneal ovarian cancer. A small percentage of ovarian cancer issues originate in the peritoneum which is bodily tissue which is separate and distinct from the ovaries. The peritoneum is a thin membrane that surrounds, protects, and helps support the stomach organs including all of the reproductive organs.


Epithelial Ovarian Cancers
The most common types of ovarian cancer are the epithelial cancers, all that are found in the epithelium — the layer of tissue that surrounds the ovary. Within this group are the following subtypes:


Serous cell epithelial ovarian cancer
This is the most frequent subtype of all epithelial ovarian cancer, accounting for approximately 60% of newly discovered cases of ovarian cancer. When diagnosed, serous cell epithelial ovarian cancer is commonly classified as either low grade or high-grade determined by the nuclei and mitotic characteristics of the cells.


Endometrioid ovarian cancer
This subtype is known by its relationship to the endometrium, which is the membrane which is the interior lining of the uterus. Endometrioid ovarian cancer could often develop in conjunction with other cancers, diseases, or abnormalities which may affect the endometrium such as endometriosis.


Mucinous, Clear Cell, and Unclassified/Undifferentiated
These 3 are less common subtypes of ovarian cancer. Though recognizable for diagnostic purposes, the prescribed treatment for each of them is similar.


Peritoneal Ovarian Cancers
Peritoneal ovarian cancer originates outside of the ovaries, in one or more areas of the peritoneum tissue. It could move to other areas in the abdomen which includes, in some cases, the ovaries. The peritoneum is a membrane that covers, guards, and assists in the supporting of the abdominal organs that includes, for women, the uterus and all of the other female reproductive organs. The peritoneum consists of epithelial cells and, in this manner, is similar to the epithelium tissue that encapsulates the ovaries. Due to this, treatment of epithelial and peritoneal cancers is frequently similar. However, peritoneal cancer can be confined to the peritoneum and not affect the ovaries. It could develop in women who have had their ovaries removed. Primary peritoneal cancer might appear anywhere in the peritoneum and not include the ovaries.

Peritoneal ovarian cancer generally means that cancer cells are present in each of the peritoneum and one or both ovaries. The serous cell lining of the ovaries and the serous cell composition of the peritoneum communicate with each other and, in this manner, cancer cells may move, through shedding or other processes, between the two. When cancer cells are present in both of the ovaries and the peritoneum, the diagnosis is peritoneal ovarian cancer.

Staging of Ovarian Cancers
When ovarian cancer is diagnosed, peritoneal, it is then staged to determine its severity and possible treatment options. A frequent ovarian cancer staging protocol is as follows:

Stage I — Growth of the cancer is limited to the ovary or ovaries.

Stage IA — Growth is limited to one ovary and the tumor is limited to the interior of the ovary. There is no cancer on the outer surface of the ovary. There are no ascites present that contain malignant cells. The capsule is intact.

Stage IB — Presence is limited to both ovaries minus any tumor on their outer surfaces. There are no ascites observed containing malignant cells. The capsule is intact.

Stage IC — The tumor is classified as either Stage IA or IB and one or more of the following are present: tumor is observed on the outer surface of one or both ovaries; the capsule has ruptured; and there are ascites that contain malignant cells or with positive peritoneal washings.

Stage II — Growth of the cancer includes one or both ovaries with pelvic extension.

Stage IIA — The cancer has extended to and involves the uterus or the fallopian tubes, or both.

Stage IIB — The cancer has extended to other pelvic organs.

Stage IIC — The tumor is classified as either Stage IIA or IIB and one or more of the following appear: tumor is present on the outer surface of one or both ovaries; the capsule has ruptured; and there are ascites that include malignant cells or with positive peritoneal washings.

Stage III — Presence of the cancer includes one or both ovaries, and one or both of the following are present: the cancer has extended past the pelvis to the lining of the abdomen; and the cancer has expanded to lymph nodes. The tumor is confined to the true pelvis but with histologically proven malignant extension to the small bowel or omentum.

Stage IIIA — During the staging operation, the doctor might observe cancer including one or both of the ovaries, yet no cancer is grossly visible in the abdomen and it has not moved to lymph nodes. However, when biopsies are checked under a microscope, very tiny amounts of cancer are discovered in the abdominal peritoneal surfaces.

Stage IIIB — The tumor is in one or both ovaries, and traces of cancer are present in the abdomen that are large enough for the doctor to see but not bigger than 2 cm in diameter. The cancer hasn’t migrated to the lymph nodes.

Stage IIIC — The tumor is in one or both ovaries, and one or both of the following is present: the cancer has migrated to lymph nodes; and the deposits of cancer exceed 2 cm in diameter and are found in the abdomen.

Stage IV — This is the most advanced stage of ovarian cancer. Presence of the cancer includes one or both ovaries and distant metastases have happened. Discovering ovarian cancer cells in pleural fluid is also evidence of stage IV disease.

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